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Common SMTP Response Codes Decoded

A quick reference guide to 250, 451, 550, and other common SMTP server responses.

Standard Success Codes

250 OK: Every sender's favorite code. The mail server has accepted the message and will attempt delivery.

Temporary Failures (4xx Series)

  • 421: Service not available, closing transmission channel. Usually means the server is rebooting or overloaded.
  • 450: Mailbox unavailable (temporarily busy or locked).
  • 451: Requested action aborted: local error in processing.

Permanent Failures (5xx Series)

  • 550 User Unknown: The most common error. The email address does not exist.
  • 554 Transaction Failed: Often triggered by spam filters or blacklists.
  • 535 Authentication Failed: Your SMTP credentials are wrong.

Need to test a server's response? Our API Documentation shows you how to integrate these checks directly into your application.

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